Analgesic property of ambulant leaves (nephalium lappaceum, sapindaceae) in comparison with pooping pod (ruellia tuberosa, Acanthaceae) syrup / Erl Dane B. Balderas, Jeralyn G. Castillo, Christine Judith P. Ducusin, Caroline Pioquinto; faculty researcher, Beverly A. Gagayao

By: Contributor(s): Publication details: 2018. : Description: xvii, 107 leaves : color illustrations ; 29 cmSubject(s): DDC classification:
  • PHA-TH 00027 B19 2018
Contents:
Plants have been used for medicinal purposes long before recorded history. It is assumed that they have medicinal properties: therefore seeds, leaves, stem, barks, roots, flowers and extracts of all of these have been used in herbal medicine over the millennia of their use. The researchers opted to use rambutan ( Nephelium lappaceum, Sapindacea) to compare with popping pod (Ruellia tuberosa, Acanthaceae) to know which plant has more analgesic property. According to Traditional Chinese Medicine (TCM), rambutan is known as effective painkiller by drinking the juice of rambutan leaves. While for a popping pod, in folk medicine, it has been used as a diuretic, antipyretic, analgesic and anti-hypertensive. Since both rambutan and popping pod have an analgesic activity, the researchers compared which plant is more effective in treating pain by using Writhing test and Plantar test. After administration of Ibuprofen (positive control), Distilled water (negative control), Rambutan, Popping pod and the combined Rambutan and Popping pod syrups, the rats were subjected into two tests, to determine the analgesic property of the plants. In writhing test, acetic acid was induced in the intraperitoneum of the rats. For scoring purposes, a "writhe" in a rat was indicated by stretching or contraction of the abdomen. Each manifestation was counted as one writhe. In plantar test, exposure to heat to the paw of the rats was done. A typical withdrawal response due to the heat should be accompanied by a rat licking its paw. Results and Discussion. Based on the data gathered in writhing test, the less number of writhes means the syrup is more effective. The lowest was the combined Rambutan and Popping pod with a mean of 3.50. In plantar test, the increase of time shows the syrup is more effective. The highest was the combined Rambutan and Popping pod with a mean of 5.60. The data were compared, and statistics showed that there are no significant differences between Ibuprofen and the formulated syrups. Conclusions. Using the highest safe dilution each syrup, the most effective syrups was produced by the group treated with the combined Rambutan and Popping pod with a mean of 3.50 om Writhing test and 5.60 in Plantar test. Therefore, the combined Rambutan and Popping pod is the most effective among syrups but lesser effcetive than Ibuprofen.
Dissertation note: Thesis (unpublished)--Lorma Colleges, San Fernando City, La Union, 2018.
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Thesis Lorma Colleges Learning Commons - CHS Campus College Thesis PHA-TH 00027 B19 2018 (Browse shelf(Opens below)) Available PHA-TH00027

Thesis (unpublished)--Lorma Colleges, San Fernando City, La Union, 2018.

Includes bibliographical references.

Plants have been used for medicinal purposes long before recorded history. It is assumed that they have medicinal properties: therefore seeds, leaves, stem, barks, roots, flowers and extracts of all of these have been used in herbal medicine over the millennia of their use. The researchers opted to use rambutan ( Nephelium lappaceum, Sapindacea) to compare with popping pod (Ruellia tuberosa, Acanthaceae) to know which plant has more analgesic property. According to Traditional Chinese Medicine (TCM), rambutan is known as effective painkiller by drinking the juice of rambutan leaves. While for a popping pod, in folk medicine, it has been used as a diuretic, antipyretic, analgesic and anti-hypertensive. Since both rambutan and popping pod have an analgesic activity, the researchers compared which plant is more effective in treating pain by using Writhing test and Plantar test.
After administration of Ibuprofen (positive control), Distilled water (negative control), Rambutan, Popping pod and the combined Rambutan and Popping pod syrups, the rats were subjected into two tests, to determine the analgesic property of the plants. In writhing test, acetic acid was induced in the intraperitoneum of the rats. For scoring purposes, a "writhe" in a rat was indicated by stretching or contraction of the abdomen. Each manifestation was counted as one writhe. In plantar test, exposure to heat to the paw of the rats was done. A typical withdrawal response due to the heat should be accompanied by a rat licking its paw.

Results and Discussion. Based on the data gathered in writhing test, the less number of writhes means the syrup is more effective. The lowest was the combined Rambutan and Popping pod with a mean of 3.50. In plantar test, the increase of time shows the syrup is more effective. The highest was the combined Rambutan and Popping pod with a mean of 5.60. The data were compared, and statistics showed that there are no significant differences between Ibuprofen and the formulated syrups.

Conclusions. Using the highest safe dilution each syrup, the most effective syrups was produced by the group treated with the combined Rambutan and Popping pod with a mean of 3.50 om Writhing test and 5.60 in Plantar test. Therefore, the combined Rambutan and Popping pod is the most effective among syrups but lesser effcetive than Ibuprofen.

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